RNAi is the best way to effectively knockdown gene expression to study cellular message in the absence of gene message. Traditional methods for knockdown in mammalian cells involved the use of synthetic RNA duplexes consisting of 2 19mers annealed together.

Stealth™ RNAi improves upon traditional methods by using proprietary chemical modifications to duplexes to ensure better RNAi results.

Find the right Invitrogen product and service for your RNAi experiments using the RNAi Application Advisor.


New Products from Invitrogen for RNAi Research Include:

Stealth RNAi which is the next generation in synthetic RNAi duplexes provides effective knockdown, higher specificity, greater stability and also greater avoidance of the stress response. Stealth RNAi is suitable for analysis in mammalian cells and animal models.

Oligonucleotide Technologies for RNAi.  Transient short-interfering RNA (siRNA) are available for RNAi analysis in mammalian cells.

Vector RNAi Technologies are available for the delivery of short-hairpin RNA (shRNA) into any mammalian cell type or animal models.

In Vitro Production for RNAi involves the transient delivery of pools of diced siRNA (d-siRNA) in mammalian cells and for RNAi in invertebrate models.